The goal of the Johannsen Lab is to understand the complex mechanisms that the Epstein-Barr virus (EBV) has evolved to exploit infected cells as an important basis for therapy of EBV-associated diseases. Our research focuses on the molecular biology and host interactions of many important proteins of EBV and their roles in both the lytic and latent stages of the EBV life cycle. We utilize many techniques, such as whole genome sequencing, transcriptomics, and genome editing to investigate the ways in which EBV precisely manipulates the growth and survival signaling pathways of B lymphocytes, resulting in their immortalization and cancer association.
Explore our lab website to learn more about what we do!
Key words: Epstein-Barr Virus, gamma herpesvirus, lymphoma, bioinformatics, cloning, genome editing
Lab Philosophy
Our lab is about discovery. We hope that these discoveries will prove useful, but it is essential that they are scientifically sound. The lab will never prioritize personal success over integrity and scientific rigor. We respect each other, our collaborators, and our competitors. We acknowledge prior research by citing it and discussing it in a collegial environment. Finally, the lab must be a safe and welcoming place for all persons.
Our Research
Our Members
For Prospective Students:
Over the years, the Johannsen lab has been host to many exceptional undergraduate, graduate, and post-doctoral trainees. We are seeking highly motivated individuals eager to gain hands-on training in viral genome mutagenesis, next generation sequencing, tissue culture, and bioinformatics as it relates to EBV-associated diseases and therapeutic targets. If you are interested in participating in the research happening in this lab, the best way learn about availability is to contact Dr. Eric Johannsen.
For more information regarding admission to UW-Madison, follow the links to either the Graduate Admissions or Undergraduate Admissions websites.