Below are highlighted the recent publications of the last several years. To find a full list of the collaborative efforts of Dr. Eric Johannsen in recent years as well as his past publications, perform a PubMed search for Dr. Eric Johannsen’s publications.
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Principle Investigator
Host Interactions:
- Epstein-Barr Virus Induces Host Shutoff extensively via BGLF5-independent mechanisms. PMID: 39298313
- EBV Reactivation from Latency Is a Degrading Experience for the Host. PMID: 36992435
- Epstein-Barr virus nuclear antigen 3C (EBNA3C) interacts with the metabolism sensing C-terminal binding protein (CtBP) repressor to upregulate host genes. PMID: 33720992
Lytic Reactivation:
- Rta is the principal activator of Epstein-Barr virus epithelial lytic transcription. PMID: 36174106
- An Epigenetic Journey: Epstein-Barr Virus Transcribes Chromatinized and Subsequently Unchromatinized Templates during Its Lytic Cycle. PMID: 30700606
EBV transcriptomics:
- Accurate Quantification of Overlapping Herpesvirus Transcripts from RNA Sequencing Data. PMID: 34705568
- CAGE-seq analysis of Epstein-Barr virus lytic gene transcription: 3 kinetic classes from 2 mechanisms. PMID: 29864140
Other:
- Epstein-Barr Virus Infection Promotes Epithelial Cell Growth by Attenuating Differentiation-Dependent Exit from the Cell Cycle. PMID: 31431547
- Pharmcards – Review Cards for Medical Students, 5th edition. ISBN-13: 978-1496384287
Collaborations
Gumperz Lab (UW-Madison):
- Human CD4(+) iNKT cell adoptive immunotherapy induces anti-tumour responses against CD1d-negative EBV-driven B lymphoma. PMID: 38736328
Kenney Lab (UW-Madison):
- Epstein-Barr virus LMP1 protein promotes proliferation and inhibits differentiation of epithelial cells via activation of YAP and TAZ. PMID: 37155846
- Type 1 and Type 2 Epstein-Barr viruses induce proliferation, and inhibit differentiation, in infected telomerase-immortalized normal oral keratinocytes. PMID: 36190982
- Reduced IRF4 expression promotes lytic phenotype in Type 2 EBV-infected B cells. PMID: 35472072
- ΔNp63α promotes Epstein-Barr virus latency in undifferentiated epithelial cells. PMID: 34748616
- Hippo signaling effectors YAP and TAZ induce Epstein-Barr Virus (EBV) lytic reactivation through TEADs in epithelial cells. PMID: 34339458
- EBNA2-deleted Epstein-Barr virus (EBV) isolate, P3HR1, causes Hodgkin-like lymphomas and diffuse large B cell lymphomas with type II and Wp-restricted latency types in humanized mice. PMID: 32542010
- An EBNA3A-Mutated Epstein-Barr Virus Retains the Capacity for Lymphomagenesis in a Cord Blood-Humanized Mouse Model. PMID: 32132242
- B cells infected with Type 2 Epstein-Barr virus (EBV) have increased NFATc1/NFATc2 activity and enhanced lytic gene expression in comparison to Type 1 EBV infection. PMID: 32059024
- An EBNA3C-deleted Epstein-Barr virus (EBV) mutant causes B-cell lymphomas with delayed onset in a cord blood-humanized mouse model. PMID: 30125329
- A cancer-associated Epstein-Barr virus BZLF1 promoter variant enhances lytic infection. PMID: 30052684
- Differentiation-Dependent LMP1 Expression Is Required for Efficient Lytic Epstein-Barr Virus Reactivation in Epithelial Cells. PMID: 28179525
- Restricted TET2 Expression in Germinal Center Type B Cells Promotes Stringent Epstein-Barr Virus Latency. PMID: 28003489
Mertz Lab (UW-Madison):
- Hypoxia-inducible factor-1α plays roles in Epstein-Barr virus’s natural life cycle and tumorigenesis by inducing lytic infection through direct binding to the immediate-early BZLF1 gene promoter. PMID: 28617871
Luftig Lab (Duke):
- Epstein-Barr virus ensures B cell survival by uniquely modulating apoptosis at early and late times after infection. PMID: 28425914